Scientific Program

Conference Series LLC Ltd invites all the participants across the globe to attend 2nd International Conference on Pediatrics, Neonatology and Healthcare Amsterdam | Netherlands.

Day 1 :

Pediatric Healthcare 2020 International Conference Keynote Speaker Maria Bertha Romo Almanza photo
Biography:

Pediatrician Neonatologist with 11 years of experience in the field, antecedent of being Cheaf in charge in Neonatal Care Intensive Unit in Hospital Star Médica Luna Parc (until 2015) and the last 5 years. Cheaf in Charge of NICU at HMI Guadalupe Victoria Atizapan, (Actually).  subspecialty of neonatology at the National Institute of Perinatology, (INPER) Graduated from UNAM, professor of advanced breastfeeding diploma APROLAM section of Neonatology, Instructor of Neonatal Resuscitation Course, Private Clinical Clinical Researcher 11 years of experience. Certified by the National Council of Neonatology in Mexico, Member of Association of Neonatologists of the State of Mexico (ANEM) and Mexican Society of Pediatrics (SMP) Publications various.

Abstract:

Background:

In recent decades, advances in medicine and its neonatal approach have allowed an increase in the survival of critically ill newborns hospitalized in NICU.

In 2018  Mexico registered  a total of 2,162,535 births, of which 50.8% correspond to the male sex and 49.2% to the female (Dates obtained by the INEGI: National Statistics Institute) with a  birth rate   17.8% (2017), Specialized Care Centers have been created in the management of newborns with some type of pathology, the challenge being now the decrease in associated comorbidity, as well as decrease hospital stay  time.

Objective:  To analyze how the maternal breastfeeding roll, kangaroo breast program and the hand washing strategies, help to reduce morbi - mortality and hospital stay in the NICU

Therefore, strategies have been sought: such as greater contact of the mother-child binomial through starting the kangaroo mom program as soon as the patient's conditions allow it, this in addition to the generated emotional bond, generates adequate microbiota presence by skin-to-skin contact. In addition to improving the weight increase day by day. Start of early feeding with human milk, through homologous donation of milk, with full support for breastfeeding, as well as pasteurization of donated human milk, and certify as a Child and Mother Friendly Hospital,

Results: During the year 2018 there were a total of 3585 births of which 8.89% (n = 319) required hospitalization The main reason for hospital admission was and is currently : prematurity, and one of its comorbidities  associated is sepsis, so another strategy that has been taken is 100% continuous training and reminders of it , to both the staff in charge of the babies, as well as the their parents, which has had a positive impact on reducing nosocomial infections,  and  a home delivery is allowed earlier. 

Pediatric Healthcare 2020 International Conference Keynote Speaker Pedro Ivan Barrera Martinez photo
Biography:

Pedro Ivan Barrera Martinez is the Head of the Neonatal Intensive Care Unite Private children´s Hospital Mexico.

Abstract:

Introduction: One of the biggest hits of neonatology in recent years has been the progress made in the preterm newborn care, however, prematurity remains the main problem of contemporary neonatology. In premature infants, is of great importance, due to its morbidity, the group of ventilated infants. Ventilation has been a neonatal intensive care technology that has contributed to the decline in infant mortality, especially in very low birth weight infants. However, changes in long-term neurodevelopmental not descend.  One possible explanation is that ventilatory practices as useful when used in a proportionate and appropriate can damage the developing brain when used excessively (eg. hypocarbia, hyperoxia). So, the question is: what can we do to protect the developing brain?

Objective: Demonstrate abnormal neurodevelopment in premature infants weighing less than 1500 grams that showed changes in levels of CO2 and O2 by ventilation.

Methods: Performing a case-control study at the National Institute of Perinatology to assess the association between neurodevelopmental disorders and CO2 and O2 by ventilation. The study was conducted with 249 infants (100%) receiving mechanical ventilation and monitoring neurodevelopmental Pediatric tracking service, with 124 cases (abnormal neurodevelopment) and 125 controls (normal neurodevelopment) which assesses the neurodevelopment at 3 years patients age infants less than 1500 grams who required ventilatory assistance at birth and showed changes in CO2 and O2 related.

Results: We analyzed the cases and controls found no statistically significant differences in terms of demographic variables (sex, weight, gestational age, length of stay, days of ventilation and minute Apgar) Table 1. In descriptive statistics found a sex distribution of 134 (53.8%) female and 115 (46.2%) male, mean gestational age of 28.81 weeks and a mean weight of 967.18 grams.

Tracking neurodevelopmental assessment was performed with the Terman-Merril, Bayles II, Amieltison, and ultrasound transfontanelar (UST). Diagnosis was altered neurodevelopment according to Terman Merrill test, normality found in 125 (50.2%). According to the result of UST were reported normal 128 (51.4%), with Grade I hemorrhage in 23 (9.2%), Grade II 48 (19.3%) and 50 (20%) with periventricular priventricular. The Bayley Scale of development, the mental scale 76 (30.5%) had less than 69 points scoring with significant delay, 69 (27.7%) were 70 to 84 points qualifying slight delay, 95 (38.2%) with a score between 85 and 114 reported normal development and 9 (3.6%) were rated with a score higher than 115 estimating accelerated development. As for the motor scale 103 (41.4%) had less than 69 points scoring with significant delay, 63 (25.3%) were 70 to 84 points qualifying slight delay, 82 (32.9%) with a score between 85 and 114 reported development normal and 1 (0.4%) were rated with a score higher than 115 estimating accelerated development. Valuing Amiel-Tison reported abnormality in 177 infants (71.1%) and was normal in 72 infants report (28.9%). In motion abnormalities 40 (20%) patients had PCI.

To qualify hypocarbia association was identified (Figure 1), hypercarbia (Figure 2), hypoxia (Figure 3) and hyperoxia (Figure 4) with normal and abnormal neurodevelopment, with statistical significance for hypercarbia (OR 9061, IC 95% 4.895-16.775, p 0.0001), hyperoxia (OR 4820, IC 95% 2.642-8.794, p 0.0001). Following the methodology outlined in Table 2 presents the results of the estimation using bivariate logistic regression, after removal of non-significant variables. First, it is noteworthy that the statistic applied to evaluate the validity of the model as a whole indicates that there are sufficient reasons to accept its validity (omnibus test of the model shows the following results: Chi Square: 146.452,   p: 0.0001), we can say the altered levels of oxygen and carbon dioxide explain abnormal neurodevelopment. In addition, Table 3 presents the results another tests commonly used to assess the goodness of fit of a logistic regression model (called Hosmer and Lemeshow). From the results it is interesting to note the high ability of the model to correctly classify infants studied. Thus, 84.3% of cases globally considered, was well rated. And there are differences between the percentages for normal children and children 86.2 82.5 abnormal.

Conclusions: The neurodevelopmental be assessed routinely in the neonatal intensive care hospital units, with strict criteria for monitoring and assessment programs established. Alterations CO2 y O2 predict positive and statistically significant association with a population-attributable risk for neurodevelopmental disorders in both OR and in the logistic regression. The neurological assessment should be used early for timely intervention. Valuing Bayley II supports reports in the literature most affected motor scale than mental. Since its initial use neonatal ventilatory support has contributed to the increased survival in the newborn and is currently a priority need for effective strategies gentle ventilation characterized by low tidal volumes, permissive hypercarbia and hypoxemia that impact short long term care and the evolution of lung neonatal neurodevelopment.